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What if…

Instead of being mere conduits of the central nervous system's commands, peripheral nerves are independent biological actors and even decision makers?

It turns out…

That from tumors to gut inflammation and other areas of disease, nerves are functioning in ways far beyond canonical contexts and mechanisms—the tissues they permeate make use of biochemical neural pathways and signals.

Founded by Flagship Pioneering in 2017, Cygnal Therapeutics is the first company to build a platform to develop drugs in the new field of exoneural biology, an unprecedented way of thinking about nerves and neural pathways outside of traditional neurobiology. Exoneural biology is broadly implicated in human health and disease.

Fueled by its Exoneural Medicines Platform™, Cygnal is creating new medicines across multiple therapeutic areas, starting with cancer and inflammatory diseases.

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