Selventa Strengthens Intellectual Property for System Diagnostics (SysDx™) Approach to Personalized Medicine

Selventa Strengthens Intellectual Property for System Diagnostics (SysDx™) Approach to Personalized Medicine

May 8, 2013

CAMBRIDGE, Mass.--(BUSINESS WIRE)--

Selventa today announced that it has been granted United States patent (No. No 8,417,661) titled “Method for Quantifying Amplitude of a Response of a Biological Network.” This patent is core to Selventa’s SysDx™ approach to mining and comparing biological data for predicting a patient’s response or non-response to a drug.

“We are very pleased to gain this important intellectual property protection that strengthens our SysDx approach to understanding a patient’s disease and predicting response or non-response to a therapy,” said David de Graaf, CEO of Selventa. “This patent is a significant step forward in the development of SysDx tests in multi-factorial diseases such as rheumatoid arthritis, IBD, and cancer. It also strengthens our leadership position in analyzing ‘big data’ molecular information to identify patient disease-relevant biomarkers.”

A major differentiator of SysDx tests is their ability to incorporate and analyze ALL relevant molecular information in a disease, across thousands of patients, to identify biomarkers that are linked to disease-driving mechanisms.

“In order to deliver true personalized medicine, physicians will require diagnostics that holistically integrate and interpret multiple types of biological data. SysDx tests consist of biomarkers that are selected through a rigorous biomarker analysis of a patient’s biological map derived from large, multi-omic data sets that can include genomic, epigenomic, transcriptomic, proteomic, metabolomic, electronic medial record information. This comprehensive analysis is then used to generate a clinically-relevant diagnostic report that physicians and patients can use to make an optimal treatment decision,” concluded de Graaf.

About Selventa

Selventa is pioneering the development of Systems Diagnostics (SysDx(TM)). This novel approach to diagnostic development harnesses a comprehensive range of complex, biological information (genomic, epigenomic, transcriptomic, proteomic, metabolomic, electronic medial records) to generate a clinically relevant dashboard that physicians, patients and researchers can use to make an optimal treatment decision or stratify patient populations.

SysDx tests are enabled by Selventa's "Big Data" analytics engine that integrates, processes, and analyzes the molecular information from thousands of patients to identify biomarkers linked to disease-driving mechanisms. SysDx tests are differentiated by their ability to capture a holistic picture of a patient's disease and drug-response profile. This is in contrast to MDx tests that are limited by their focus on a particular class of biological analytes (e.g. genomics-only tests). This superior predictive and prognostic value is required in the diagnosis of complex multi-factorial diseases such as autoimmune disease and cancer.

For more information, visit www.selventa.com.